Hardin Scientific | News Portal -
Controlling and visualizing receptor signals in neural cells with light
Feb, 14th 2019, 07:00 from eurekalert.org
This new tool is a true two-in-one solution. In future, it might help to study a number of diseases. Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualised serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in the eye, namely melanopsin. As a result, they were able to switch the receptor on and off using light; it also acted like a sensor indicating via fluorescence if specific signalling pathways...

Read More



New DNA methylation GrimAge tool allows you to predict lifespan and healthspan
Feb, 13th 2019, 09:14 from news-medical.net
The Grim Reaper arrives for each of us eventually--wouldn't it be nice to know when? Now UCLA researchers have developed a new tool to help you plan ahead for your date with the Angel of Death. Named after the grim reaper, the biomarker known as DNA methylation GrimAge, allows one to predict lifespan and healthspan, and to test potential interventions that may slow or perhaps even reverse biological aging. The journal Aging publishes the findings. Ake Lu and Steve Horvath from the Department of ...

Read More



VUMC researchers, supercomputing effort reveal antibody secrets
Feb, 13th 2019, 07:00 from eurekalert.org
Using sophisticated gene sequencing and computing techniques, researchers at Vanderbilt University Medical Center (VUMC) and the San Diego Supercomputer Center have achieved a first-of-its-kind glimpse into how the body's immune system gears up to fight off infection. Their findings, published this week in the journal Nature, could aid development of "rational vaccine design," as well as improve detection, treatment and prevention of autoimmune diseases, infectious diseases, and cancer. "Due to ...

Read More



Researchers map extremely complex chromosome aberrations using DNA puzzle pieces
Feb, 12th 2019, 10:41 from news-medical.net
Using puzzle pieces from four different DNA analyses, researchers at Karolinska Institutet in Sweden have been able to map three extremely complex chromosome aberrations. This has given families answers about the cause of their children's serious symptoms. The study was published in the scientific journal PLOS Genetics and the goal is to produce a test to be used in the clinic. One in 500 people carries a balanced chromosome aberration. It means having all the genetic make-up but not in the righ...

Read More



Researchers uncover mechanism of protein transport in mitochondria
Feb, 7th 2019, 15:21 from phys.org
Mitochondria play a fundamental role for the metabolism of the cell. They produce the main energy for cellular functions and are therefore known as the powerhouse of the cell. Defects in mitochondrial metabolism cause a number of severe diseases of the heart, muscle or nerve systems. Mitochondrial function depends on the exchange of metabolites with the surrounding cell. Therefore, metabolites have to be transported across the two surrounding membranes. The voltage-dependent anion channel porin/...

Read More



Ebola antibody treatment tested in people
Feb, 5th 2019, 02:00 from nih.gov
The Ebola virus causes severe illness and is often fatal. Early symptoms include fever, headache, body aches, weakness, stomach pain, and lack of appetite. Later, it can cause vomiting, diarrhea, and severe bleeding. No treatments have been approved yet, but supportive care can improve survival. Ebola outbreaks in Africa are challenging settings to deliver treatments, but researchers have made progress evaluating potential therapies. ZMapp, which is a combination of three proteins called monoclo...

Read More



New insights into plant cell organelle and molecule movement
Feb, 4th 2019, 15:57 from phys.org
The TGN is at the intersection of pathways that control molecule traffic into (endocytosis) and out of (exocytosis) the plant cell. The TGN and its network of supportingexpand iconproteins are essential to proper metabolism many organisms. But their function remains a mystery to scientists. We do know that the TGN contributes to building upexpand iconplant biomass, which is important for plant-based products, like fuels, food, and animal feed. In humans, TGN defects cause neurodegenerative d...

Read More



A Simple Migration/Invasion Workflow Using an Automated Live-cell Imager | Protocol
Feb, 2nd 2019, 21:00 from jove.com
Cell migration and invasion are important biological processes that enable normal functions in the human body, such as wound closure, invasion of placenta into the uterus and mammary gland morphogenesis1,2,3. The human body has precise and strict control of these biological events; however, there are some exceptions. Malignant tumors, for example, are able to escape this safeguard, exhibit abnormal proliferation and invade into neighboring tissue, which is called metastasis. Metastasis is the ma...

Read More



Quantifying the Heterogeneous Distribution of a Synaptic Protein in the Mouse Brain Using Immunofluorescence | Protocol
Jan, 29th 2019, 20:00 from jove.com
  CITE THIS  SHARE  The presence, absence, or levels of specific synaptic proteins can severely influence synaptic transmission. In addition to elucidating the function of a protein, it is vital to also determine its distribution. Here, we describe a protocol employing immunofluorescence, confocal microscopy, and computer-based analysis to determine the distribution of the synaptic protein Mover (also called TPRGL or SVAP30). We compare the distribution of Mover to that of the syna...

Read More



Making 'sense' of the 'cart before the horse' in mammalian cells
Jan, 28th 2019, 23:12 from medicalxpress.com
A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome. When the fusion gene is transcribed into RNA, the product is a fusion RNA that then is translated into a fusion protein. Fusion proteins may lead to cancer development. For instance, they are found in some types of cancer such as leukemia, prostate, breast, lung and others,...

Read More



Targeted antisense oligonucleotide drug tested in humans
Jan, 28th 2019, 07:00 from eurekalert.org
New Rochelle, NY, January 28, 2019--A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers. Click here to read the full-text article free on the Nucleic Acid Ther...

Read More



Genetic Engineering of Dictyostelium discoideum Cells Based on Selection and Growth on Bacteria | Protocol
Jan, 25th 2019, 21:00 from jove.com
Dictyostelium discoideum is an intriguing model organism for the study of cell differentiation processes during development, cell signaling, and other important cellular biology questions. The technologies available to genetically manipulate Dictyostelium cells are well-developed. Transfections can be performed using different selectable markers and marker re-cycling, including homologous recombination and insertional mutagenesis. This is supported by a well-annotated genome. However, these appr...

Read More



Researchers uncover new role of heterochromatin in maintaining chromosomal integrity
Jan, 24th 2019, 12:17 from news-medical.net
A team led by researchers at Osaka University finds that extra-tight packaging of genomic material helps prevent large chromosomal rearrangements that can lead to cancer Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes in the structure of chromosomes, known as gross chromosomal rearrangements, can result in cell death or gen...

Read More



Anticancer immunity through tumor antigen identification & conversion to DNA vaccines
Jan, 24th 2019, 07:00 from eurekalert.org
PHILADELPHIA -- (Jan. 24, 2019) -- Wistar scientists and collaborators demonstrated the utility of an optimized synthetic DNA vaccine platform for rapidly inducing immunity against unique combinations of tumor neoantigens. These results reveal a direct pathway to effectively tackling the tumor variability that presents enormous challenges for the development of effective immune strategies. This study, published online in Cancer Immunology Research, advanced the techniques for rapidly screening ...

Read More



Harvest of Endothelial Cells from the Balloon Tips of Swan-Ganz Catheters after Right Heart Catheterization | Protocol
Jan, 23rd 2019, 21:00 from jove.com
A variety of pathologies lead to pulmonary hypertension (PH), which is defined as a mean pulmonary artery pressure exceeding 25 mmHg at rest. To further diagnose and manage PH, patients undergo repeated right heart catheterizations (RHC) wherein a Swan-Ganz catheter is advanced into a branch of the pulmonary artery and a balloon is inflated to wedge the catheter tip. This article illustrates a protocol whereby pulmonary artery endothelial cells (PAECs) may be harvested from the balloon tips of S...

Read More



Lab-Scale Clarification of Mammalian Cell Cultures Expressing Recombinant Antibodies
Jan, 23rd 2019, 11:37 from news-medical.net
Sponsored Content by Sartorius Lab Instruments GmbH & Co. KGJan 23 2019 insights from industry Tina Stoschek & Marcus Gerlach Research, Development & Lab Management Tubulis Technologies An interview with Tina Stoschek and Marcus Gerlach, discussing maximizing monoclonal antibody generation using lab-scale clarification of mammalian cell cultures expressing recombinant antibodies. Monoclonal antibodies are increasingly important as targeted therapeutics. Please give an overview of this indus...

Read More



Team uses synthetic biology to elucidate the complexities of cell function
Jan, 23rd 2019, 09:35 from phys.org
In addition to membrane-encased organelles—the nucleus, mitochondria, and Golgi apparatus, to name a few—eukaryotic cells harbor a variety of compartments that lack a casing. These protein-based liquid globules, called membraneless organelles, carry out various cellular functions that would be less efficient or not possible at all in the cytoplasm. And researchers are now learning that membraneless organelles could play a role in the aggregation of proteins associated with disease, for example A...

Read More



Advances in 3D and organoid cell culture
Jan, 23rd 2019, 07:00 from eurekalert.org
A new collection of reviews and original research articles in SLAS Technology illustrate how new technologies and advanced cell culture are accelerating basic research, drug discovery and drug development. When cultured under 3D conditions, human induced pluripotent stem cells (iPSCs) provide optimized systems that more accurately reflect disease-related target mutations, compound pharmacology and toxicology. The review articles in this collection feature a comprehensive, two-part, overview of ...

Read More



Beckman Coulter launches new ClearLLab 10C System for clinical flow cytometry lab
Jan, 17th 2019, 13:23 from news-medical.net
Jan 17 2019 Reviewed by Kate Anderton, B.Sc. Beckman Coulter launches the ClearLLab 10C System for the clinical flow cytometry lab. The new system includes the first 10-color CE-IVD panels of immunophenotyping reagents for both lymphoid and myeloid lineages. The tubes utilize DURA Innovations dry reagent technology for the panels, which requires no refrigeration. Alongside the panels, the integrated ClearLLab 10C system comprises: The ClearLLab 10C System incorporates the company’s new Kaluza...

Read More



Salk team uses new model to study health effects of AMP-activated protein kinase
Jan, 16th 2019, 10:04 from news-medical.net
The metabolic protein AMPK has been described as a kind of magic bullet for health. Studies in animal models have shown that compounds that activate the protein have health-promoting effects to reverse diabetes, improve cardiovascular health, treat mitochondrial disease--even extend life span. However, how much of the effects of these compounds can be fully attributed to AMPK versus other potential targets is unknown. Now, Salk researchers have developed a new system that lets them study in more...

Read More



Study: Induced neuronal cells derived from fibroblasts are similar to neurons in the brain
Jan, 16th 2019, 07:38 from news-medical.net
The incidence of some neurological diseases--especially those related to aging, such as Alzheimer's and Parkinson's diseases--is increasing. To better understand these conditions and evaluate potential new treatments, researchers need accurate models that they can study in the lab. Researchers from the Salk Institute, along with collaborators at Stanford University and Baylor College of Medicine, have shown that cells from mice that have been induced to grow into nerve cells using a previously p...

Read More



DNA origami: A precise measuring tool for optimal antibody effectiveness
Jan, 15th 2019, 13:42 from phys.org
Scientists at Karolinska Institutet, Sweden, in collaboration with researchers at University of Oslo, Norway, have demonstrated the most accurate distance between densely packed antigens in order to get the strongest bond to antibodies in the immune system. The study, which is published in the journal Nature Nanotechnology, may be of significance to the development of vaccines and immunotherapy used in cancer. Vaccines work by training the immune system with harm...

Read More



DNA origami can accurately measure how antibodies interact with several antigens
Jan, 14th 2019, 18:55 from news-medical.net
Using DNA origami - DNA-based design of precise nanostructures - scientists at Karolinska Institutet in collaboration with researchers at University of Oslo, have been able to demonstrate the most accurate distance between densely packed antigens in order to get the strongest bond to antibodies in the immune system. The study, which is published in the journal Nature Nanotechnology, may be of significance to the development of vaccines and immunotherapy used in cancer. Vaccines work by training ...

Read More



New discovery casts doubt on plasma membrane models
Jan, 14th 2019, 12:19 from news-medical.net
Like planets, the body's cell surfaces look smooth from a distance but hilly closer up. An article published in Communications Biology describes implications, unknown to date, of the way data from cell surfaces are normally interpreted; i.e. as if they lacked topographic features. When Earth is studied from space, its surface looks smooth, but on zooming in we notice the mountains and valleys. The same applies to cells; without magnification they look smooth, but a closer look reveals both ridge...

Read More



Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues | Protocol
Jan, 10th 2019, 21:00 from jove.com
With the development of high throughput single cell technology1,2 and advancements in user-friendly bioinformatics tools over the last decade3, a new field of high-resolution gene expression analysis has emerged – single-cell RNA sequencing (scRNA-Seq). The study of single cell gene expression was first developed to identify heterogeneity within defined cell populations, such as in stem cells or cancer cells, or to identify rare populations of cells4,5, which were unattainable using traditional ...

Read More



Identification of Functional Protein Regions Through Chimeric Protein Construction | Protocol
Jan, 8th 2019, 22:00 from jove.com
The goal of this protocol encompasses the design of chimeric proteins in which distinct regions of a protein are replaced by their corresponding sequences in a structurally similar protein, in order to determine the functional importance of these regions. Such chimeras are generated by means of a nested PCR protocol using overlapping DNA fragments and adequately designed primers, followed by their expression within a mammalian system to ensure native secondary structure and post-translational mo...

Read More



Stem cells used to trace autism back to the formation of neurons
Jan, 8th 2019, 21:45 from arstechnica.com
While autism is a spectrum of disorders, it's clear that the more significant cases involve physical differences in the brain's nerve cells. Several studies have reported an excess in connections among neurons in the brains of people with autism. But when does this happen? Changes in neural connections are key components of learning and memory, and they can happen at any point in life; major reorganizations in connectivity occur from before birth up to the late teens. Anecdotal reports of autism...

Read More



Feeding Your Immune System - Keeping Your Mitochondria Healthy
Jan, 8th 2019, 14:11 from thrive-magazine.co.uk
Nourishing your mitochondria may be fundamental to staying healthy this winter. Thrive Expert Victoria Hamilton gives some tips on keeping these power houses inside our cells in tip top shape. You may have come across the word ‘mitochondria’ recently or perhaps you recall it from a school biology lesson and know that its associated with your cells and energy production in the body. It’s a new area of focus in human health and not without due cause. A human cell is made up of many functions and o...

Read More



Generating Recombinant Avian Herpesvirus Vectors with CRISPR/Cas9 Gene Editing | Protocol
Jan, 7th 2019, 21:00 from jove.com
Herpesvirus of turkeys (HVT) is an ideal viral vector for the generation of recombinant vaccines against a number of avian diseases, such as avian influenza (AI), Newcastle disease (ND), and infectious bursal disease (IBD), using bacterial artificial chromosome (BAC) mutagenesis or conventional recombination methods. The clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 system has been successfully used in many settings for gene editing, including the manipulation of several larg...

Read More



Fujifilm Cellular Dynamics to build $21 million stem cell plant in Madison | BizTimes Media Milwaukee
Jan, 3rd 2019, 19:15 from biztimes.com
Madison-based Fujifilm Cellular Dynamics Inc. announced today it plans to build a $21 million stem cell manufacturing plant in Madison. Fujifilm Cellular Dynamics is a U.S. subsidiary of Japanese electronics manufacturer Fujifilm Corp. FCD develops and produces human induced pluripotent stem cell technologies. At the new facility, it would industrialize the process of manufacturing the stem cells for use in regenerative medicine, both directly and through contract manufacturing, the company said...

Read More



Proximity to muscle cells may promote spread of prostate cancer cells, NIH study suggests
Jan, 3rd 2019, 14:12 from medicalxpress.com
Proximity to nearby muscle cells may make prostate cancer cells more likely to invade nearby tissues and spread to other organs, according to an early study by researchers at the National Institutes of Health. The presence of muscle cells appears to make cancer cells more likely to fuse two or more cancer cells into a single cell, thereby increasing their invasiveness and ability to spread. The study was led by Berna Uygur, Ph.D., of NIH's Eunice Kennedy Shriver National Institute of Child Healt...

Read More



Researchers reveal cause of possible genetic problems in mitochondria
Jan, 3rd 2019, 13:45 from news-medical.net
A group of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) has revealed the importance of eliminating any excess of defective products that might have accumulated in the mitochondria, as its presence generates mitochondrial instability and information loss on the mitochondrial genome. The study can bring new ways to understand the molecular basis of some human diseases that are stem from poor functioning of the mitochondria and, in this way, allow...

Read More



The landscape of protein tyrosine phosphatase (Shp2) and cancer
Dec, 27th 2018, 07:00 from eurekalert.org
As the proteomics technology develops and human genomic analysis becomes easier to execute, molecules involved in the regulation of biochemical signaling pathways have become interesting subjects for researchers. Earlier research was based on assumptions that metabolic cascades such as phosphorylation was linear. However, current studies indicate a multi-network signaling cascade. The interlinked signals performing in synchrony can be observed being responsive to a stimulus during physiological ...

Read More



Autophagy and mitochondria: Targets in neurodegenerative disorders
Dec, 26th 2018, 07:00 from eurekalert.org
This article by Dr. Ashutosh Kumar et al. is published in CNS & Neurological Disorders - Drug Targets, Volume 17, Issue 9, 2018 Autophagy is a cellular degradation process that can cause the death of a cell in certain conditions. Autophagy is necessary to maintain cellular homeostasis by clearing out damaged cellular organelles and proteins through certain pathways. Mitochondria are cell organelles responsible for the constant supply of energy to maintain cellular physiology and energy metabolis...

Read More



A deeper understanding of chromosome capping could improve therapies for both cancer and aging
Dec, 20th 2018, 15:53 from medicalxpress.com
The zipper style of DNA replication means that the tips of chromosomes cannot be copied, leaving them slightly shorter with each cell division. To prevent loss of genetic information, chromosome ends are protected by caps called telomeres—repetitive, gene-free regions (see image). Each division shortens the telomeres, until they disappear and the cell can no longer divide. In cells that need to divide indefinitely, such as stem cells, an enzyme called telomerase extends telomeres, allowing cells...

Read More



Researchers uncover genes that play a key role in the inactivation of X chromosomes
Dec, 19th 2018, 14:43 from news-medical.net
In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference? Geneticists from the University of Geneva (UNIGE), Switzerland, turned to some historic research dating from the 1960s to sequence skin and blood cells one by one. They observed how the second X chromosome in females gradually becomes inactive in order to avoid an overdose of genes encoded by the X. They also found that several genes bypassed this inactivation, which...

Read More



New genetic testing technology enhances precision of analysis of clinical biomarkers
Dec, 18th 2018, 16:31 from medicalxpress.com
Estonian scientists have announced the invention of a genetic testing technology to analyse the number of clinical biomarkers at the single-molecule level, which enhances the sensitivity of tests in precision medicine and will make them more affordable in future. The TAC-seq method, for which a patent is pending, is already being used in fertility clinics to determine the personal variations in the menstrual cycle for opportune embryo transfer. The new molecular ...

Read More



Female biology – two X chromosomes and ovaries – extends life and protects mice from aging
Dec, 18th 2018, 16:01 from medicalxpress.com
Now, scientists at UC San Francisco have zeroed in on a possible genetic mechanism for this highly durable phenomenon, that – while it does not preclude the influence of other biological, social and environmental factors – suggests an important role for the second X chromosome, which is present in female mammals. The X chromosome contains many genes related to the brain, and it is crucial for survival. Without at least one X, an animal cannot live. The Y chromosome, present only in males, contai...

Read More



Inflating cells to analyze organelle structure and function
Dec, 17th 2018, 17:23 from news-medical.net
By Sally Robertson, B.Sc.Dec 17 2018 Reviewed by Kate Anderton, B.Sc. Researchers at the University of Geneva have developed a technique that enables visualization of cellular organelles at a resolution that has not previously been achievable in optical microscopy. Being able to see these structures would allow an improved understanding of how cells function, but achieving this has been a difficult challenge. Until now, fluorescence microscopy has not provided a resolution high enough to ob...

Read More



Folate deficiency creates more damaging chromosomal abnormalities than previously known
Dec, 15th 2018, 06:07 from news-medical.net
Reviewed by Kate Anderton, B.Sc.Dec 14 2018 Folate deficiency creates more problems in connection with DNA replication than researchers had hitherto assumed, researchers from the University of Copenhagen show in a new study. Once a person lacks folate, the damage caused by this cannot be reversed. The researchers therefore encourage people to be more aware of the level of folate in the blood. Folate deficiency can severely affect one of the most important processes in the body, cell division...

Read More



Montana State researcher awarded grant for research of fluorescent proteins
Dec, 14th 2018, 07:00 from eurekalert.org
BOZEMAN -- A Montana State University doctoral student who is working on a way to improve a neuroscience tool that uses fluorescent proteins found in some jellyfish and coral has received a grant that will help fund her work. The National Institute of Neurological Disorders and Stroke awarded a three-year F31 fellowship grant to Rosana Molina, a doctoral candidate in the Department of Cell Biology and Neuroscience in MSU's College of Letters and Science. The grant provides Molina with a stipend ...

Read More



Researchers explore how glial cells develop in the brain from neural precursor cells
Dec, 10th 2018, 21:02 from news-medical.net
Two types of cells are active in the brain: nerve cells and glial cells. The latter have long been regarded primarily as supportive cells, but it is increasingly recognized that they play an active role in the communication between neurons in the brain. What is more, according to current research, glial cells are also involved in the development of neurodegenerative diseases. A research team led by Professor Benedikt Berninger of the Institute of Physiological Chemistry at the Mainz University M...

Read More



Studying Protein Import into Chloroplasts Using Protoplasts | Protocol
Dec, 10th 2018, 20:00 from jove.com
The chloroplast is an essential organelle that is responsible for various cellular processes in plants, such as photosynthesis and the production of many secondary metabolites and lipids. Chloroplasts require a large number of proteins for these various physiological processes. Over 95% of chloroplast proteins are nucleus-encoded and imported into chloroplasts from the cytosol after translation on cytosolic ribosomes. Thus, the proper import or targeting of these nucleus-encoded chloroplast prot...

Read More



Study sheds new light on microtubule binding proteins and microtubule dynamics
Dec, 7th 2018, 06:40 from news-medical.net
Reviewed by Kate Anderton, B.Sc.Dec 6 2018 When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections. During T-cell activation, a molecular complex known as the microtubule-organizing center (MTOC) moves to a central location on the surface of the T-cell. Microtubules have several important functions, including determining cell shape and cell division. Thus, MTOC repositio...

Read More



Influenza A deliberately enhances levels of the human p53 protein to reduce anti-viral gene and protein expression
Nov, 30th 2018, 14:52 from medicalxpress.com
IAV remains a key challenge for global health resources, not least because of wide variations in symptom severity experienced by different people, even when they are infected by the same strain. This implies that there are host factors at play during the initial host-viral interaction. Ee Chee Ren, Bei Wang and their team at A*STAR's Singapore Immunology Network have worked for several years on the protein p53, which plays various roles in cancer, cellular stress responses, and host anti-viral r...

Read More



Researchers produce six antibodies to combat Zika virus
Nov, 29th 2018, 07:00 from eurekalert.org
MAYWOOD, IL - Researchers have generated six Zika virus antibodies that could be used to test for and possibly treat a mosquito-borne disease that has infected more than 1.5 million people worldwide. The antibodies "may have the dual utility as diagnostics capable of recognizing Zika virus subtypes and may be further developed to treat Zika virus infection," corresponding author Ravi Durvasula, MD, and colleagues report in a study published in the journal PLOS ONE. Dr. Durvasula is professor and...

Read More



Study reveals why mitochondria are often strangely shaped inside the brain
Nov, 28th 2018, 10:32 from news-medical.net
Reviewed by James Ives, MPsychNov 28 2018 Columbia neuroscientists have discovered why mitochondria, tiny power generators that keep our cells healthy, are often strangely shaped inside the brain. Mitochondria, which exist by the thousands in each of our body's 37 trillion cells, usually look like long interconnected tubes. But inside brain cells called neurons, they adopt two completely different shapes depending on their location within the cell: that same elongated, tubular shape and a su...

Read More



First probabilistic atlas of thalamus nuclei to better understand the brain
Nov, 20th 2018, 20:21 from news-medical.net
A multidisciplinary study led by BCBL, a Basque research center, opens the door to the investigation of the structure and functions of human thalamic nuclei and their involvement in Alzheimer's, dyslexia, epilepsy, Huntington's and schizophrenia. The thalamus is one of the most important structures in the human brain. Its nuclei distribute the information of the motor apparatus and of all the senses of the human being, with the sole exception of smell. In addition, they are involved in many func...

Read More



A new atlas of the thalamus nuclei to better understand the brain
Nov, 20th 2018, 15:55 from medicalxpress.com
The thalamus is one of the most important structures in the human brain. Its nuclei distribute the information of the motor apparatus and of all the senses of the human being, with the sole exception of smell. In addition, they are involved in many functions such as attention, awareness and perception. It´s importance is such that, if injured, the individual in question can go into a coma. Until now, whenever the activity of the thalamus was recorded, experts could only review it as a whole, wit...

Read More